phenobarbital will minimize the extent or effect of aprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

phenobarbital will decrease the level or result of saxagliptin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.

phenobarbital will lower the extent or outcome of paclitaxel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.

Sodium valproate and valproic acid enhance the phenobarbital serum ranges; hence, phenobarbital blood levels ought to be closely monitored and suitable dosage changes built as clinically indicated.

Effectively managing pentobarbital withdrawal commences whenever a clinician recognizes the individual is both liable to or struggling from withdrawal. When withdrawal is suspected, the interprofessional workforce should coordinate affected person care by:

phenobarbital will lower the level or effect of eplerenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Mysterious.

phenobarbital will minimize the extent or result of buprenorphine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

phenobarbital will minimize the level or outcome of larotrectinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

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bremelanotide will reduce the level or impact of phenobarbital by Other (see comment). Stay clear of or Use Alternate check here Drug. Bremelanotide may slow gastric emptying and potentially reduces the speed and extent of absorption of concomitantly administered oral remedies.

phenobarbital will reduce the extent or result of atogepant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Recommended atogepant dosage with concomitant utilization of powerful or reasonable CYP3A4 inducers is thirty mg or 60 mg qDay.

phenobarbital will decrease the extent or effect of cobicistat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. If coadministration is necessary, watch for deficiency or loss of virologic reaction from cobicistat

Overdosage: If you believe you've got taken far too much of the medicine Speak to a poison Management Middle or emergency home at once.

Usage in Pediatric Clients. Phenobarbital has long been claimed being connected to cognitive deficits in little ones using it for complicated febrile seizures.